Polynucleotides
Teach your skin to repair itself.
The regenerative treatment everyone's asking about: purified salmon DNA that switches your skin back into repair mode. Extraordinary for tired under-eyes.
Regeneration, not disguise.
Filler adds volume; polynucleotides do something cleverer. These purified DNA fragments, remarkably compatible with human skin, signal your fibroblasts to produce fresh collagen and elastin, calm inflammation, and deeply hydrate from within. The skin doesn't just look better; it genuinely behaves younger.
‘Didn’t you sleep last night?’ If you’re asked that after a full eight hours, this is your treatment. The under-eye area is where polynucleotides shine. Dark, crepey, hollow-looking eyes are often unsafe or unsuitable for filler, but respond beautifully to regeneration, brightening and thickening delicate skin over a short course.
Yes, it comes from salmon — and yes, everyone asks. It's precisely because salmon DNA is so similar to ours that it's accepted by the skin without reaction. Results build over weeks and improve with each session; we recommend a course of two or three, spaced a few weeks apart, then a top-up around every six months.
What happens at your appointment
- Skin assessment: under-eyes, cheeks, neck or wherever quality has dipped.
- Numbing cream while the product comes to temperature.
- A pattern of tiny superficial injections across the area.
- Tiny blebs settle within 24–48 hours; the glow builds over the following weeks.
Medically reviewed by Katie, Independent Nurse Prescriber · July 2026
Good to know
Questions, answered honestly.
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